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The primary mission of the Seattle Structural Genomics Center for Infectious Disease (SSGCID) is to establish a resource for gene-to-structure research focused ...
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CSGID is a consortium of laboratories using state-of-the-art structural biology methods to determine the 3-D structures of proteins from pathogens in the NIAID ...
Missing: Alpha- Beta Function
Seattle Structural Genomics Center for Infectious Disease ... Alpha-proteobacteria ( Anaplasma, Bartonella ... Beta-proteobacteria ( Burkholderia ); Chlamydiae ...
Sep 17, 2010 · ... fold, which is a single alpha/beta domain with the dinucleotide binding “Rossmann” fold, characteristic for the SCD/R family. The rmsd of ...
Jul 15, 2021 · AlphaFold greatly improves the accuracy of structure prediction by incorporating novel neural network architectures and training procedures ...
... alpha-beta domains. The active site patch is formed between the two beta sheets, one each from the middle domain and the the C-terminal domain. Functional ...
These simple folds provide a wide range of possibilities for function. In order to study this diversity, it helps to have a large dataset of structures to ...
Oct 26, 2009 · We are currently witnessing an explosion in technological and computational advances in structural genomics, with protein structures of hundreds ...
Here we report on the progress of our structural genomics program aiming at the discovery of new antibacterial gene targets among evolutionary conserved genes ...
Sep 17, 2010 · We have determined 1.7 Angstrom resolution crystal structure of an acyl carrier protein S-malonyltransferase from the V. cholerae Ol biovar ...